Cargando…

EGFP-EGF1-conjugated poly (lactic-co-glycolic acid) nanoparticles as a carrier for the delivery of CCR2− shRNA to atherosclerotic macrophage in vitro

Reducing macrophage recruitment by silencing chemokine (C–C motif) receptor 2 (CCR2) expression is a promising therapeutic approach against atherosclerosis. However the transfection of macrophages with siRNA is often technically challenging. EGFP-EGF1-conjugated poly (lactic-co-glycolic acid) (PLGA)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Zhilin, Chen, Chen, Luo, Jiajia, Davis, Jacques R. J., Zhang, Bo, Tang, Liang, Shi, Wei, Liao, Danying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661524/ https://www.ncbi.nlm.nih.gov/pubmed/33184330 http://dx.doi.org/10.1038/s41598-020-76416-4

Ejemplares similares

EGFP-EGF1-conjugated poly(lactic-co-glycolic acid) nanoparticles, a new diagnostic tool and drug carrier for atherosclerosis
por: Wu, Zhilin, et al.
Publicado: (2019)

Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for DNA, shRNA and siRNA
por: Arima, Hidetoshi, et al.
Publicado: (2012)

Specific properties of shRNA-mediated CCR5 downregulation that enhance the inhibition of HIV-1 infection in combination with shRNA targeting HIV-1 rev
por: Cardona, Maria E., et al.
Publicado: (2022)

CCR3-shRNA promotes apoptosis and inhibits chemotaxis and degranulation of mouse mast cells
por: Peng, Haisen, et al.
Publicado: (2020)

Biologically responsive carrier-mediated anti-angiogenesis shRNA delivery for tumor treatment
por: Che, Junyi, et al.
Publicado: (2016)

Characterization of a potent non-cytotoxic shRNA directed to the HIV-1 co-receptor CCR5
por: Shimizu, Saki, et al.
Publicado: (2009)

Downregulation of mouse CCR3 by lentiviral shRNA inhibits proliferation and induces apoptosis of mouse eosinophils
por: Zhu, Xin-Hua, et al.
Publicado: (2017)

Construction of shRNA lentiviral vector
por: Song, Hong, et al.
Publicado: (2010)

Optimized PCR Conditions and Increased shRNA Fold Representation Improve Reproducibility of Pooled shRNA Screens
por: Strezoska, Žaklina, et al.
Publicado: (2012)

EGFP-EGF1-Conjugated PLGA Nanoparticles for Targeted Delivery of siRNA into Injured Brain Microvascular Endothelial Cells for Efficient RNA Interference
por: Chen, Chen, et al.
Publicado: (2013)

shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library
por: Kamatuka, Kenta, et al.
Publicado: (2016)

Targeting of sialoadhesin-expressing macrophages through antibody-conjugated (polyethylene glycol) poly(lactic-co-glycolic acid) nanoparticles
por: Van Hees, Sofie, et al.
Publicado: (2022)

Improved siRNA/shRNA Functionality by Mismatched Duplex
por: Wu, Haoquan, et al.
Publicado: (2011)

A tissue factor-cascade-targeted strategy to tumor vasculature: a combination of EGFP-EGF1 conjugation nanoparticles with photodynamic therapy
por: Shi, Wei, et al.
Publicado: (2016)

Biodegradable poly (lactic acid-co-glycolic acid) scaffolds as carriers for genetically-modified fibroblasts
por: Perisic, Tatjana, et al.
Publicado: (2017)

Conjugation of cell-penetrating peptides with poly(lactic-co-glycolic acid)-polyethylene glycol nanoparticles improves ocular drug delivery
por: Vasconcelos, Aimee, et al.
Publicado: (2015)

Delivery of Therapeutic AGT shRNA by PEG-Bu for Hypertension Therapy
por: Wang, Yu-Qiang, et al.
Publicado: (2013)

CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection
por: Anderson, Joseph, et al.
Publicado: (2005)

Correction: A tissue factor-cascade-targeted strategy to tumor vasculature: a combination of EGFP-EGF1 conjugation nanoparticles with photodynamic therapy
por: Shi, Wei, et al.
Publicado: (2018)

Optimization and characterization of tRNA-shRNA expression constructs
por: Scherer, Lisa J., et al.
Publicado: (2007)

Design and cloning strategies for constructing shRNA expression vectors
por: McIntyre, Glen J, et al.
Publicado: (2006)

The effects of stem length and core placement on shRNA activity
por: Mcintyre, Glen J, et al.
Publicado: (2011)

Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design
por: Matveeva, Olga V., et al.
Publicado: (2010)

Energy profile and secondary structure impact shRNA efficacy
por: Zhou, Hong, et al.
Publicado: (2009)

Production of Transgenic Calves Expressing an shRNA Targeting Myostatin
por: Tessanne, K, et al.
Publicado: (2012)

Suppression of Cancer Progression by MGAT1 shRNA Knockdown
por: Beheshti Zavareh, Reza, et al.
Publicado: (2012)

Using shRNA experiments to validate gene regulatory networks
por: Olsen, Catharina, et al.
Publicado: (2015)

Silencing Human Rb2/p130 with shRNA
por: Leucci, Eleonora, et al.
Publicado: (2007)

Stable expression of shRNA for the control of recombinant adenovirus replication
por: Lana, M.V.G., et al.
Publicado: (2023)

Carriers of rare damaging CCR2 genetic variants are at lower risk of atherosclerotic disease
por: Georgakis, Marios K., et al.
Publicado: (2023)

Cetuximab-Conjugated Magnetic Poly(Lactic-co-Glycolic Acid) Nanoparticles for Dual-Targeted Delivery of Irinotecan in Glioma Treatment
por: Dash, Banendu Sunder, et al.
Publicado: (2023)

Efficient and Non-Toxic Biological Response Carrier Delivering TNF-α shRNA for Gene Silencing in a Murine Model of Rheumatoid Arthritis
por: Song, Jialin, et al.
Publicado: (2016)

Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
por: Lu, Yue, et al.
Publicado: (2023)

Criteria for effective design, construction, and gene knockdown by shRNA vectors
por: Taxman, Debra J, et al.
Publicado: (2006)

Single copy shRNA configuration for ubiquitous gene knockdown in mice
por: Seibler, Jost, et al.
Publicado: (2005)

PCR-based generation of shRNA libraries from cDNAs
por: Du, Cheng, et al.
Publicado: (2006)

Letter to the editor: Does Dicer Expression Affect shRNA processing?
por: Senzer, Neil, et al.
Publicado: (2009)

Nucleic acid aptamers for targeting of shRNA-based cancer therapeutics
por: Vorhies, John S, et al.
Publicado: (2007)

A comparison of multiple shRNA expression methods for combinatorial RNAi
por: Mcintyre, Glen J, et al.
Publicado: (2011)

ShRNA-Targeted COMMD7 Suppresses Hepatocellular Carcinoma Growth
por: Zheng, Lu, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_8omjruq4n57b6gg82elkp0oat6