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A ‘Split-Gene’ Transketolase From the Hyper-Thermophilic Bacterium Carboxydothermus hydrogenoformans: Structure and Biochemical Characterization

A novel transketolase has been reconstituted from two separate polypeptide chains encoded by a ‘split-gene’ identified in the genome of the hyperthermophilic bacterium, Carboxydothermus hydrogenoformans. The reconstituted active α(2)β(2) tetrameric enzyme has been biochemically characterized and its...

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Detalles Bibliográficos
Autores principales: James, Paul, Isupov, Michail N., De Rose, Simone Antonio, Sayer, Christopher, Cole, Isobel S., Littlechild, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661550/
https://www.ncbi.nlm.nih.gov/pubmed/33193259
http://dx.doi.org/10.3389/fmicb.2020.592353