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PTRH2: an adhesion regulated molecular switch at the nexus of life, death, and differentiation

Peptidyl-tRNA hydrolase 2 (PTRH2; Bit-1; Bit1) is an underappreciated regulator of adhesion signals and Bcl2 expression. Its key roles in muscle differentiation and integrin-mediated signaling are central to the pathology of a recently identified patient syndrome caused by a cluster of Ptrh2 gene mu...

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Detalles Bibliográficos
Autores principales: Corpuz, Austin D., Ramos, Joe W., Matter, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661711/
https://www.ncbi.nlm.nih.gov/pubmed/33298880
http://dx.doi.org/10.1038/s41420-020-00357-0