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PTRH2: an adhesion regulated molecular switch at the nexus of life, death, and differentiation
Peptidyl-tRNA hydrolase 2 (PTRH2; Bit-1; Bit1) is an underappreciated regulator of adhesion signals and Bcl2 expression. Its key roles in muscle differentiation and integrin-mediated signaling are central to the pathology of a recently identified patient syndrome caused by a cluster of Ptrh2 gene mu...
Autores principales: | Corpuz, Austin D., Ramos, Joe W., Matter, Michelle L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661711/ https://www.ncbi.nlm.nih.gov/pubmed/33298880 http://dx.doi.org/10.1038/s41420-020-00357-0 |
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