Human transcription factors responsive to initial reprogramming predominantly undergo legitimate reprogramming during fibroblast conversion to iPSCs

The four transcription factors OCT4, SOX2, KLF4, and MYC (OSKM) together can convert human fibroblasts to induced pluripotent stem cells (iPSCs). It is, however, perplexing that they can do so only for a rare population of the starting cells with a long latency. Transcription factors (TFs) define id...

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Detalles Bibliográficos
Autores principales: Cevallos, Ricardo R., Edwards, Yvonne J. K., Parant, John M., Yoder, Bradley K., Hu, Kejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661723/
https://www.ncbi.nlm.nih.gov/pubmed/33184372
http://dx.doi.org/10.1038/s41598-020-76705-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661723/
https://www.ncbi.nlm.nih.gov/pubmed/33184372
http://dx.doi.org/10.1038/s41598-020-76705-y

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