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LncRNA HULC shRNA disinhibits miR-377-5p to suppress the growth and invasion of hepatocellular carcinoma in vitro and hepatocarcinogenesis in vivo

BACKGROUND: Aberrant expression of up-regulated long non-coding RNA [LncRNA highly upregulated in liver cancer (HULC)] has been observed to play an important regulatory role in the development of multiple human diseases. However, the molecular mechanism underlying the role of HULC and miR-377-5p in...

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Detalles Bibliográficos
Autores principales: Yan, Chunxiao, Wei, Shutang, Han, Dazheng, Wu, Liping, Tan, Lixia, Wang, Hangyu, Dong, Yong, Hua, Jing, Yang, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661872/
https://www.ncbi.nlm.nih.gov/pubmed/33209874
http://dx.doi.org/10.21037/atm-20-5556