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Long non-coding RNA TRPM2-AS sponges microRNA-138-5p to activate epidermal growth factor receptor and PI3K/AKT signaling in non-small cell lung cancer

BACKGROUND: Long non-coding RNAs (lncRNAs) can play pivotal roles in tumor progression by acting as microRNA (miRNA) sponges. This study aimed to investigate the association of a novel lncRNA, TRPM2-AS, with the miR-138-5p/EGFR axis in the development of non-small cell lung cancer (NSCLC). METHODS:...

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Detalles Bibliográficos
Autores principales: Cui, Dong, Feng, Yu, Shi, Kefeng, Zhang, Huimin, Qian, Rulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661873/
https://www.ncbi.nlm.nih.gov/pubmed/33209893
http://dx.doi.org/10.21037/atm-20-6331