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Artesunate alleviates myocardial ischemia/reperfusion-induced myocardial necrosis in rats and hypoxia/reoxygenation-induced apoptosis in H9C2 cells via regulating the FAK/PI3K/Akt pathway

BACKGROUND: The various anti-inflammatory, anti-apoptotic, and antioxidant effects of Artesunate (Art) have been explored in numerous studies. This study aimed to evaluate the function of Art on myocardial necrosis in apoptotic cardiomyocytes in vivo and in vitro. METHODS: Sprague Dawley (SD) rats w...

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Detalles Bibliográficos
Autores principales: Fan, Shunyang, Zhang, Deyin, Liu, Fuyun, Yang, Yuqi, Xu, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661874/
https://www.ncbi.nlm.nih.gov/pubmed/33209871
http://dx.doi.org/10.21037/atm-20-5182