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Fine particulate matter exposure promotes M2 macrophage polarization through inhibiting histone deacetylase 2 in the pathogenesis of chronic obstructive pulmonary disease

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality globally. Fine particulate matter (PM2.5) has been indicated to be a major detrimental risk factor for COPD by numerous epidemiological studies. Histone deacetylase 2 (HDAC2), a critical regulator of...

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Detalles Bibliográficos
Autores principales: Jiang, Yan, Zhao, Yanfeng, Wang, Qingliang, Chen, Hao, Zhou, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661902/
https://www.ncbi.nlm.nih.gov/pubmed/33209883
http://dx.doi.org/10.21037/atm-20-6653