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Fibrocyte localisation to the ASM bundle in asthma: bidirectional effects on cell phenotype and behaviour

OBJECTIVES: Airway hyper‐responsiveness and persistent airflow obstruction contribute to asthma pathogenesis and symptoms, due in part to airway smooth muscle (ASM) hypercontractility and increased ASM mass. Fibrocytes have been shown to localise to the ASM in asthma however it is not known whether...

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Detalles Bibliográficos
Autores principales: Saunders, Ruth, Kaur, Davinder, Desai, Dhananjay, Berair, Rachid, Chachi, Latifa, Thompson, Richard D, Siddiqui, Salman H, Brightling, Christopher E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662089/
https://www.ncbi.nlm.nih.gov/pubmed/33209301
http://dx.doi.org/10.1002/cti2.1205