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Distinct Roles of LFA-1 and ICAM-1 on ILC2s Control Lung Infiltration, Effector Functions, and Development of Airway Hyperreactivity

Asthma is a heterogeneous airway inflammatory disease characterized by increased airway hyperreactivity (AHR) to specific and unspecific stimuli. Group 2 innate lymphoid cells (ILC2)s are type-2 cytokine secreting cells capable of inducing eosinophilic lung inflammation and AHR independent of adapti...

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Detalles Bibliográficos
Autores principales: Hurrell, Benjamin P., Howard, Emily, Galle-Treger, Lauriane, Helou, Doumet Georges, Shafiei-Jahani, Pedram, Painter, Jacob D., Akbari, Omid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662114/
https://www.ncbi.nlm.nih.gov/pubmed/33193309
http://dx.doi.org/10.3389/fimmu.2020.542818