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Tribbles Homolog 3-Mediated Vascular Insulin Resistance Contributes to Hypoxic Pulmonary Hypertension in Intermittent Hypoxia Rat Model

This study aimed to investigate the role of vascular insulin resistance (VIR) and Tribbles homolog 3 (TRIB3) in the pathogenesis of hypoxia-induced pulmonary hypertension (HPH). Rats were subjected to low air pressure and low oxygen intermittently for 4 weeks to induce HPH. The mean right ventricula...

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Detalles Bibliográficos
Autores principales: Fan, Fang, He, Jinxiao, Su, Hui, Zhang, Haifeng, Wang, Hao, Dong, Qianqian, Zeng, Minghua, Xing, Wenjuan, Sun, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662151/
https://www.ncbi.nlm.nih.gov/pubmed/33192545
http://dx.doi.org/10.3389/fphys.2020.542146