Frailty Is Associated With Neutrophil Dysfunction Which Is Correctable With Phosphoinositol-3-Kinase Inhibitors

Neutrophil dysfunction has been described with age, appears exaggerated in infection, with altered phosphoinositol signaling a potential mechanism. However, functional aging is heterogeneous. Frailty is a negative health status and is more common in older adults. We hypothesized that neutrophil migr...

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Detalles Bibliográficos
Autores principales: Wilson, Daisy, Drew, William, Jasper, Alice, Crisford, Helena, Nightingale, Peter, Newby, Paul, Jackson, Thomas, Lord, Janet M, Sapey, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662170/
https://www.ncbi.nlm.nih.gov/pubmed/32877922
http://dx.doi.org/10.1093/gerona/glaa216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662170/
https://www.ncbi.nlm.nih.gov/pubmed/32877922
http://dx.doi.org/10.1093/gerona/glaa216

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