Molecular Modeling Study of c-KIT/PDGFRα Dual Inhibitors for the Treatment of Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are the most common Mesenchymal Neoplasm of the gastrointestinal tract. The tumorigenesis of GISTs has been associated with the gain-of-function mutation and abnormal activation of the stem cell factor receptor (c-KIT) and platelet-derived growth factor recept...

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Detalles Bibliográficos
Autores principales: Keretsu, Seketoulie, Ghosh, Suparna, Cho, Seung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662224/
https://www.ncbi.nlm.nih.gov/pubmed/33153146
http://dx.doi.org/10.3390/ijms21218232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662224/
https://www.ncbi.nlm.nih.gov/pubmed/33153146
http://dx.doi.org/10.3390/ijms21218232

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