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Expression of EMT-Related Genes in Hybrid E/M Colorectal Cancer Cells Determines Fibroblast Activation and Collagen Remodeling

Collagen, the main non-cellular component of the extracellular matrix (ECM), is profoundly reorganized during tumorigenesis and has a strong impact on tumor behavior. The main source of collagen in tumors is cancer-associated fibroblasts. Cancer cells can also participate in the synthesis of ECM; ho...

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Detalles Bibliográficos
Autores principales: Druzhkova, Irina, Shirmanova, Marina, Ignatova, Nadezhda, Dudenkova, Varvara, Lukina, Maria, Zagaynova, Elena, Safina, Dina, Kostrov, Sergey, Didych, Dmitry, Kuzmich, Alexey, Sharonov, George, Rakitina, Olga, Alekseenko, Irina, Sverdlov, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662237/
https://www.ncbi.nlm.nih.gov/pubmed/33143259
http://dx.doi.org/10.3390/ijms21218119