Enhanced Dopamine Transmission and Hyperactivity in the Dopamine Transporter Heterozygous Mice Lacking the D3 Dopamine Receptor

Dopamine transporter knockout (DATk) mice are known to demonstrate profound hyperactivity concurrent with elevated (5-fold) extracellular dopamine in the basal ganglia. At the same time, heterozygous DAT mice (DATh) demonstrate a 2-fold increase in dopamine levels yet only a marginal elevation in lo...

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Detalles Bibliográficos
Autores principales: Sotnikova, Tatyana D., Efimova, Evgeniya V., Gainetdinov, Raul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662256/
https://www.ncbi.nlm.nih.gov/pubmed/33153031
http://dx.doi.org/10.3390/ijms21218216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662256/
https://www.ncbi.nlm.nih.gov/pubmed/33153031
http://dx.doi.org/10.3390/ijms21218216

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