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Structural Insights into β-arrestin/CB1 Receptor Interaction: NMR and CD Studies on Model Peptides

Activation of the cannabinoid CB1 receptor induces different cellular signaling cascades through coupling to different effector proteins (G-proteins and β-arrestins), triggering numerous therapeutic effects. Conformational changes and rearrangements at the intracellular domain of this GPCR receptor...

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Detalles Bibliográficos
Autores principales: Morales, Paula, Bruix, Marta, Jiménez, M. Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662265/
https://www.ncbi.nlm.nih.gov/pubmed/33143110
http://dx.doi.org/10.3390/ijms21218111