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Structural Insights into β-arrestin/CB1 Receptor Interaction: NMR and CD Studies on Model Peptides
Activation of the cannabinoid CB1 receptor induces different cellular signaling cascades through coupling to different effector proteins (G-proteins and β-arrestins), triggering numerous therapeutic effects. Conformational changes and rearrangements at the intracellular domain of this GPCR receptor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662265/ https://www.ncbi.nlm.nih.gov/pubmed/33143110 http://dx.doi.org/10.3390/ijms21218111 |