Hybridization of Curcumin Analogues with Cinnamic Acid Derivatives as Multi-Target Agents Against Alzheimer’s Disease Targets

The synthesis of the new hybrids followed a hybridization with the aid of hydroxy-benzotriazole (HOBT) and 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDCI.HCL) in dry DMF or thionyl chloride between curcumin analogues and cinnamic acid derivatives. IR, (1)H-NMR, (13)C-NMR, LC/MS ESI(+), and elem...

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Detalles Bibliográficos
Autores principales: Chainoglou, Eirini, Siskos, Argyris, Pontiki, Eleni, Hadjipavlou-Litina, Dimitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662280/
https://www.ncbi.nlm.nih.gov/pubmed/33114751
http://dx.doi.org/10.3390/molecules25214958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662280/
https://www.ncbi.nlm.nih.gov/pubmed/33114751
http://dx.doi.org/10.3390/molecules25214958

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