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B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats

Intra-renal tertiary lymphoid organs (TLOs) are associated with worsened outcome in kidney transplantation (Ktx). We used an anti-BAFF (B cell activating factor) intervention to investigate whether BAFF is required for TLO formation in a full MHC-mismatch Ktx model in rats. Rats received either ther...

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Detalles Bibliográficos
Autores principales: Steines, Louisa, Poth, Helen, Herrmann, Marlene, Schuster, Antonia, Banas, Bernhard, Bergler, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662293/
https://www.ncbi.nlm.nih.gov/pubmed/33126753
http://dx.doi.org/10.3390/ijms21218045