Increased Skeletal Muscle Fiber Cross-Sectional Area, Muscle Phenotype Shift, and Altered Insulin Signaling in Rat Hindlimb Muscles in a Prenatally Androgenized Rat Model for Polycystic Ovary Syndrome

Women with polycystic ovary syndrome (PCOS) are reported to have greater lean mass and insulin resistance. To examine muscular changes in a prenatally androgenized (PNA) rat model for PCOS, Sprague–Dawley rats were exposed to 5 mg testosterone or vehicle daily on gestational days 16–19. At 15 weeks...

Descripción completa

Detalles Bibliográficos
Autores principales: DeChick, Auryana, Hetz, Rebecca, Lee, Jack, Speelman, Diana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662395/
https://www.ncbi.nlm.nih.gov/pubmed/33113794
http://dx.doi.org/10.3390/ijms21217918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662395/
https://www.ncbi.nlm.nih.gov/pubmed/33113794
http://dx.doi.org/10.3390/ijms21217918

Ejemplares similares