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Pathogenic Differences of Type 1 Restriction-Modification Allele Variants in Experimental Listeria monocytogenes Meningitis

Background: L. monocytogenes meningoencephalitis has a mortality rate of up to 50% and neurofunctional sequelae are common. Type I restriction-modification systems (RMS) are capable of adding methyl groups to the host genome. Some contain multiple sequence recognition (hsdS) genes that recombine, re...

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Detalles Bibliográficos
Autores principales: Zbinden, Florian R., De Ste Croix, Megan, Grandgirard, Denis, Haigh, Richard D., Vacca, Irene, Zamudio, Roxana, Goodall, Emily C. A., Stephan, Roger, Oggioni, Marco R., Leib, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662400/
https://www.ncbi.nlm.nih.gov/pubmed/33194838
http://dx.doi.org/10.3389/fcimb.2020.590657