Non-canonical Interaction Between O-Linked N-Acetylglucosamine Transferase and miR-146a-5p Aggravates High Glucose-Induced Endothelial Inflammation

Background and Aims: Increased O-GlcNAc transferase (OGT)–induced O-linked N-acetylglucosamine (O-GlcNAc) post-translational modification is linked with diabetic complications. MicroRNA-146a-5p (miR-146a-5p) is a negative inflammatory regulator and is downregulated in diabetes. Here, we investigated...

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Detalles Bibliográficos
Autores principales: Lo, Wan-Yu, Wang, Shou-Jie, Wang, Huang-Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662465/
https://www.ncbi.nlm.nih.gov/pubmed/33192537
http://dx.doi.org/10.3389/fphys.2020.01091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662465/
https://www.ncbi.nlm.nih.gov/pubmed/33192537
http://dx.doi.org/10.3389/fphys.2020.01091

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