Pyrazole Incorporated New Thiosemicarbazones: Design, Synthesis and Investigation of DPP-4 Inhibitory Effects

Dipeptidyl peptidase-4 (DPP-4) inhibition has been recognized as a promising approach to develop safe and potent antidiabetic agents for the management of type 2 diabetes. In this context, new thiosemicarbazones (2a–o) were prepared efficiently by the reaction of aromatic aldehydes with 4-[4-(1H-pyr...

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Detalles Bibliográficos
Autores principales: Sever, Belgin, Soybir, Hasan, Görgülü, Şennur, Cantürk, Zerrin, Altıntop, Mehlika Dilek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662656/
https://www.ncbi.nlm.nih.gov/pubmed/33126761
http://dx.doi.org/10.3390/molecules25215003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662656/
https://www.ncbi.nlm.nih.gov/pubmed/33126761
http://dx.doi.org/10.3390/molecules25215003

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