Optimization of Mouse Growth Hormone Plasmid DNA Electrotransfer into Tibialis Cranialis Muscle of “Little” Mice

Previous non-viral gene therapy was directed towards two animal models of dwarfism: Immunodeficient (lit/scid) and immunocompetent (lit/lit) dwarf mice. The former, based on hGH DNA administration into muscle, performed better, while the latter, a homologous model based on mGH DNA, was less efficien...

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Detalles Bibliográficos
Autores principales: Rosa Lima, Eliana, Regina Cecchi, Claudia, Higuti, Eliza, Protasio Pacheco de Jesus, Gustavo, Moura Gomes, Alissandra, Aparecido Zacarias, Enio, Bartolini, Paolo, Nunes Peroni, Cibele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662792/
https://www.ncbi.nlm.nih.gov/pubmed/33142961
http://dx.doi.org/10.3390/molecules25215034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662792/
https://www.ncbi.nlm.nih.gov/pubmed/33142961
http://dx.doi.org/10.3390/molecules25215034

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