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Optimization of Mouse Growth Hormone Plasmid DNA Electrotransfer into Tibialis Cranialis Muscle of “Little” Mice
Previous non-viral gene therapy was directed towards two animal models of dwarfism: Immunodeficient (lit/scid) and immunocompetent (lit/lit) dwarf mice. The former, based on hGH DNA administration into muscle, performed better, while the latter, a homologous model based on mGH DNA, was less efficien...
Autores principales: | Rosa Lima, Eliana, Regina Cecchi, Claudia, Higuti, Eliza, Protasio Pacheco de Jesus, Gustavo, Moura Gomes, Alissandra, Aparecido Zacarias, Enio, Bartolini, Paolo, Nunes Peroni, Cibele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662792/ https://www.ncbi.nlm.nih.gov/pubmed/33142961 http://dx.doi.org/10.3390/molecules25215034 |
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