Inhibition of Yes-Associated Protein by Verteporfin Ameliorates Unilateral Ureteral Obstruction-Induced Renal Tubulointerstitial Inflammation and Fibrosis

Yes-associated protein (YAP) activation after acute ischemic kidney injury might be related to interstitial fibrosis and impaired renal tubular regeneration. Verteporfin (VP) is a photosensitizer used in photodynamic therapy to treat age-related macular degeneration. In cancer cells, VP inhibits TEA...

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Detalles Bibliográficos
Autores principales: Jin, Jixiu, Wang, Tian, Park, Woong, Li, Wenjia, Kim, Won, Park, Sung Kwang, Kang, Kyung Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662854/
https://www.ncbi.nlm.nih.gov/pubmed/33142952
http://dx.doi.org/10.3390/ijms21218184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662854/
https://www.ncbi.nlm.nih.gov/pubmed/33142952
http://dx.doi.org/10.3390/ijms21218184

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