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Signaling via the Interleukin-10 Receptor Attenuates Cardiac Hypertrophy in Mice During Pressure Overload, but not Isoproterenol Infusion

Inflammation plays a key role during cardiac hypertrophy and the development of heart failure. Interleukin-10 (IL-10) is a major anti-inflammatory cytokine that is expressed in the heart and may play a crucial role in cardiac remodeling. Based on the evidence that IL-10 potentially reduces pathologi...

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Detalles Bibliográficos
Autores principales: Stafford, Nicholas, Assrafally, Farryah, Prehar, Sukhpal, Zi, Min, De Morais, Ana M., Maqsood, Arfa, Cartwright, Elizabeth J., Mueller, Werner, Oceandy, Delvac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662881/
https://www.ncbi.nlm.nih.gov/pubmed/33192505
http://dx.doi.org/10.3389/fphar.2020.559220