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A Cleavable C(2)-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes

[Image: see text] Bioorthogonal chemistry is bridging the divide between static chemical connectivity and the dynamic physiologic regulation of molecular state, enabling in situ transformations that drive multiple technologies. In spite of maturing mechanistic understanding and new bioorthogonal bon...

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Detalles Bibliográficos
Autores principales: Wilkovitsch, Martin, Haider, Maximilian, Sohr, Barbara, Herrmann, Barbara, Klubnick, Jenna, Weissleder, Ralph, Carlson, Jonathan C. T., Mikula, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662912/
https://www.ncbi.nlm.nih.gov/pubmed/33119297
http://dx.doi.org/10.1021/jacs.0c07922