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Label-Free Oligonucleotide-Based SPR Biosensor for the Detection of the Gene Mutation Causing Prothrombin-Related Thrombophilia

Prothrombin-related thrombophilia is a genetic disorder produced by a substitution of a single DNA base pair, replacing guanine with adenine, and is detected mainly by polymerase chain reaction (PCR). A suitable alternative that could detect the single point mutation without requiring sample amplifi...

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Detalles Bibliográficos
Autores principales: Sierpe, Rodrigo, Kogan, Marcelo J., Bollo, Soledad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663036/
https://www.ncbi.nlm.nih.gov/pubmed/33142935
http://dx.doi.org/10.3390/s20216240