Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3

Extracellular signal-regulated kinase 3 (ERK3), known also as mitogen-activated protein kinase 6 (MAPK6), is an atypical member of MAPK kinase family, which has been poorly studied. Little is known regarding its function in biological processes, yet this atypical kinase has been suggested to play im...

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Detalles Bibliográficos
Autores principales: Schröder, Martin, Filippakopoulos, Panagis, Schwalm, Martin P., Ferrer, Carla A., Drewry, David H., Knapp, Stefan, Chaikuad, Apirat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663056/
https://www.ncbi.nlm.nih.gov/pubmed/33114754
http://dx.doi.org/10.3390/ijms21217953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663056/
https://www.ncbi.nlm.nih.gov/pubmed/33114754
http://dx.doi.org/10.3390/ijms21217953

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