Cargando…

Synthetic Route to Glycosyl β-1C-(phosphino)-phosphonates as Unprecedented Stable Glycosyl Diphosphate Analogs and Their Preliminary Biological Evaluation

The synthesis of glycosyl-β-1C-(phosphino)-phosphonates is a challenge since it has not yet been described. In this paper, we report an innovative synthetic method for their preparation from Glc-, Man-, and GlcNAc- lactone derivatives. The proposed original strategy involves the addition of the corr...

Descripción completa

Detalles Bibliográficos
Autores principales: Bosco, Michaël, Paik, Su-Jin, Busca, Patricia, Moore, Stuart E. H., Gravier-Pelletier, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663146/
https://www.ncbi.nlm.nih.gov/pubmed/33121078
http://dx.doi.org/10.3390/molecules25214969