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Vitamin B3-Based Biologically Active Compounds as Inhibitors of Human Cholinesterases

We evaluated the potential of nine vitamin B3 scaffold-based derivatives as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors, as a starting point for the development of novel drugs for treating disorders with cholinergic neurotransmission-linked pathology. As the results indic...

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Detalles Bibliográficos
Autores principales: Zandona, Antonio, Lihtar, Gabriela, Maraković, Nikola, Miš, Katarina, Bušić, Valentina, Gašo-Sokač, Dajana, Pirkmajer, Sergej, Katalinić, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663184/
https://www.ncbi.nlm.nih.gov/pubmed/33138280
http://dx.doi.org/10.3390/ijms21218088