Cargando…

The Synthetic Flavonoid Derivative GL-V9 Induces Apoptosis and Autophagy in Cutaneous Squamous Cell Carcinoma via Suppressing AKT-Regulated HK2 and mTOR Signals

Cutaneous squamous-cell carcinoma (cSCC) is one of most common type of non-black skin cancer. The malignancy degree and the death risk of cSCC patients are significantly higher than basal cell carcinoma patients. GL-V9 is a synthesized flavonoid derived from natural active ingredient wogonin and sho...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yejin, Liu, Mengdi, Yao, Jingyue, Guo, Qinglong, Wei, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663336/
https://www.ncbi.nlm.nih.gov/pubmed/33143000
http://dx.doi.org/10.3390/molecules25215033