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Effect of Tryptophan-Derived AhR Ligands, Kynurenine, Kynurenic Acid and FICZ, on Proliferation, Cell Cycle Regulation and Cell Death of Melanoma Cells—In Vitro Studies

Tryptophan metabolites: kynurenine (KYN), kynurenic acid (KYNA) and 6-formylindolo[3,2-b]carbazole (FICZ) are considered aryl hydrocarbon receptor (AhR) ligands. AhR is mainly expressed in barrier tissues, including skin, and is involved in various physiological and pathological processes in skin. W...

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Detalles Bibliográficos
Autores principales: Walczak, Katarzyna, Langner, Ewa, Makuch-Kocka, Anna, Szelest, Monika, Szalast, Karolina, Marciniak, Sebastian, Plech, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663343/
https://www.ncbi.nlm.nih.gov/pubmed/33114713
http://dx.doi.org/10.3390/ijms21217946