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Effect of Tryptophan-Derived AhR Ligands, Kynurenine, Kynurenic Acid and FICZ, on Proliferation, Cell Cycle Regulation and Cell Death of Melanoma Cells—In Vitro Studies
Tryptophan metabolites: kynurenine (KYN), kynurenic acid (KYNA) and 6-formylindolo[3,2-b]carbazole (FICZ) are considered aryl hydrocarbon receptor (AhR) ligands. AhR is mainly expressed in barrier tissues, including skin, and is involved in various physiological and pathological processes in skin. W...
Autores principales: | Walczak, Katarzyna, Langner, Ewa, Makuch-Kocka, Anna, Szelest, Monika, Szalast, Karolina, Marciniak, Sebastian, Plech, Tomasz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663343/ https://www.ncbi.nlm.nih.gov/pubmed/33114713 http://dx.doi.org/10.3390/ijms21217946 |
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