Antitumor Activity of the Cardiac Glycoside αlDiginoside by Modulating Mcl-1 in Human Oral Squamous Cell Carcinoma Cells

We recently isolated a cardiac glycoside (CG), αldiginoside, from an indigenous plant in Taiwan, which exhibits potent tumor-suppressive efficacy in oral squamous cell carcinoma (OSCC) cell lines (SCC2095 and SCC4, IC(50) < 0.2 µM; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT...

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Detalles Bibliográficos
Autores principales: Weng, Jing-Ru, Lin, Wei-Yu, Bai, Li-Yuan, Hu, Jing-Lan, Feng, Chia-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663359/
https://www.ncbi.nlm.nih.gov/pubmed/33114727
http://dx.doi.org/10.3390/ijms21217947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663359/
https://www.ncbi.nlm.nih.gov/pubmed/33114727
http://dx.doi.org/10.3390/ijms21217947

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