Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

In an effort to discover viable systemic chemotherapeutic agents for neuroendocrine tumors (NETs), we screened a small library of 18 drug-like compounds obtained from the Velu lab against pulmonary (H727) and thyroid (MZ-CRC-1 and TT) neuroendocrine tumor-derived cell lines. Two potent lead compound...

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Detalles Bibliográficos
Autores principales: Aburjania, Zviadi, Whitt, Jason D., Jang, Samuel, Nadkarni, Dwayaja H., Chen, Herbert, Rose, J. Bart, Velu, Sadanandan E., Jaskula-Sztul, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663375/
https://www.ncbi.nlm.nih.gov/pubmed/33114525
http://dx.doi.org/10.3390/molecules25214940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663375/
https://www.ncbi.nlm.nih.gov/pubmed/33114525
http://dx.doi.org/10.3390/molecules25214940

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