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Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

In an effort to discover viable systemic chemotherapeutic agents for neuroendocrine tumors (NETs), we screened a small library of 18 drug-like compounds obtained from the Velu lab against pulmonary (H727) and thyroid (MZ-CRC-1 and TT) neuroendocrine tumor-derived cell lines. Two potent lead compound...

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Detalles Bibliográficos
Autores principales:	Aburjania, Zviadi, Whitt, Jason D., Jang, Samuel, Nadkarni, Dwayaja H., Chen, Herbert, Rose, J. Bart, Velu, Sadanandan E., Jaskula-Sztul, Renata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663375/ https://www.ncbi.nlm.nih.gov/pubmed/33114525 http://dx.doi.org/10.3390/molecules25214940

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