Prolonged Immobilization Exacerbates the Loss of Muscle Mass and Function Induced by Cancer-Associated Cachexia through Enhanced Proteolysis in Mice

We hypothesized that in mice with lung cancer (LC)-induced cachexia, periods of immobilization of the hindlimb (7 and 15 days) may further aggravate the process of muscle mass loss and function. Mice were divided into seven groups (n = 10/group): (1) non-immobilized control mice, (2) 7-day unloaded...

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Detalles Bibliográficos
Autores principales: Mañas-García, Laura, Penedo-Vázquez, Antonio, López-Postigo, Adrián, Deschrevel, Jorieke, Durán, Xavier, Barreiro, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663403/
https://www.ncbi.nlm.nih.gov/pubmed/33142912
http://dx.doi.org/10.3390/ijms21218167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663403/
https://www.ncbi.nlm.nih.gov/pubmed/33142912
http://dx.doi.org/10.3390/ijms21218167

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