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Application of In Vitro Metabolism Activation in High-Throughput Screening

In vitro methods which incorporate metabolic capability into the assays allow us to assess the activity of metabolites from their parent compounds. These methods can be applied into high-throughput screening (HTS) platforms, thereby increasing the speed to identify compounds that become active via t...

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Detalles Bibliográficos
Autores principales: Ooka, Masato, Lynch, Caitlin, Xia, Menghang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663506/
https://www.ncbi.nlm.nih.gov/pubmed/33142951
http://dx.doi.org/10.3390/ijms21218182