(5-Hydroxy-4-oxo-2-styryl-4H-pyridin-1-yl)-acetic Acid Derivatives as Multifunctional Aldose Reductase Inhibitors

As rate-limited enzyme of polyol pathway, aldose reductase (ALR2) is one of the key inhibitory targets for alleviating diabetic complications. To reduce the toxic side effects of the inhibitors and to decrease the level of oxidative stress, the inhibitory selectivity towards ALR2 against detoxicatin...

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Detalles Bibliográficos
Autores principales: Chen, Huan, Zhang, Xin, Zhang, Xiaonan, Liu, Wenchao, Lei, Yanqi, Zhu, Changjin, Ma, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663616/
https://www.ncbi.nlm.nih.gov/pubmed/33158254
http://dx.doi.org/10.3390/molecules25215135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663616/
https://www.ncbi.nlm.nih.gov/pubmed/33158254
http://dx.doi.org/10.3390/molecules25215135

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