Fluid Shear Stress Induces EMT of Circulating Tumor Cells via JNK Signaling in Favor of Their Survival during Hematogenous Dissemination

Tumor cells metastasize to distal organs mainly through hematogenous dissemination, where they experience considerable levels of fluid shear stress. Epithelial–mesenchymal transition (EMT) plays a critical role in tumor metastasis. However, how fluid shear stress influences the EMT phenotype of circ...

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Detalles Bibliográficos
Autores principales: Xin, Ying, Li, Keming, Yang, Mo, Tan, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663710/
https://www.ncbi.nlm.nih.gov/pubmed/33143160
http://dx.doi.org/10.3390/ijms21218115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663710/
https://www.ncbi.nlm.nih.gov/pubmed/33143160
http://dx.doi.org/10.3390/ijms21218115

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