A Photoalkylative Fluorogenic Probe of Guttiferone A for Live Cell Imaging and Proteome Labeling in Plasmodium falciparum

Guttiferone A (GA) 1, a polycyclic polyprenylated acylphloroglucinol (PPAP) isolated from the plant Symphonia globulifera (Clusiaceae), constitutes a novel hit in antimalarial drug discovery. PPAPs do not possess identified biochemical targets in malarial parasites up to now. Towards this aim, we de...

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Detalles Bibliográficos
Autores principales: Duval, Romain, Cottet, Kevin, Blaud, Magali, Merckx, Anaïs, Houzé, Sandrine, Grellier, Philippe, Lallemand, Marie-Christine, Michel, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663766/
https://www.ncbi.nlm.nih.gov/pubmed/33158263
http://dx.doi.org/10.3390/molecules25215139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663766/
https://www.ncbi.nlm.nih.gov/pubmed/33158263
http://dx.doi.org/10.3390/molecules25215139

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