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A Photoalkylative Fluorogenic Probe of Guttiferone A for Live Cell Imaging and Proteome Labeling in Plasmodium falciparum
Guttiferone A (GA) 1, a polycyclic polyprenylated acylphloroglucinol (PPAP) isolated from the plant Symphonia globulifera (Clusiaceae), constitutes a novel hit in antimalarial drug discovery. PPAPs do not possess identified biochemical targets in malarial parasites up to now. Towards this aim, we de...
Autores principales: | Duval, Romain, Cottet, Kevin, Blaud, Magali, Merckx, Anaïs, Houzé, Sandrine, Grellier, Philippe, Lallemand, Marie-Christine, Michel, Sylvie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663766/ https://www.ncbi.nlm.nih.gov/pubmed/33158263 http://dx.doi.org/10.3390/molecules25215139 |
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