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Optimizing the Profile of [(99m)Tc]Tc–NT(7–13) Tracers in Pancreatic Cancer Models by Means of Protease Inhibitors

Background: The overexpression of neurotensin subtype 1 receptors (NTS1Rs) in human tumors may be elegantly exploited for directing neurotensin (NT)-based radionuclide carriers specifically to cancer sites for theranostic purposes. We have recently shown that [(99m)Tc]Tc–DT1 ([(99m)Tc]Tc–[N(4)–Gly(7...

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Detalles Bibliográficos
Autores principales: Kanellopoulos, Panagiotis, Nock, Berthold A., Krenning, Eric P., Maina, Theodosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663772/
https://www.ncbi.nlm.nih.gov/pubmed/33114537
http://dx.doi.org/10.3390/ijms21217926