The New Dipeptide TSPO Ligands: Design, Synthesis and Structure–Anxiolytic Activity Relationship †

The translocator protein (TSPO, 18 kDa) plays an important role in the synthesis of neurosteroids by promoting the transport of cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step in neurosteroidogenesis. Stimulation of TSPO by appropriate ligands increase...

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Detalles Bibliográficos
Autores principales: Gudasheva, Tatiana A., Deeva, Olga A., Pantileev, Andrey S., Mokrov, Grigory V., Rybina, Inna V., Yarkova, Milada A., Seredenin, Sergei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663781/
https://www.ncbi.nlm.nih.gov/pubmed/33158242
http://dx.doi.org/10.3390/molecules25215132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663781/
https://www.ncbi.nlm.nih.gov/pubmed/33158242
http://dx.doi.org/10.3390/molecules25215132

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