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Endocytosis and Trafficking of Heparan Sulfate Proteoglycans in Triple-Negative Breast Cancer Cells Unraveled with a Polycationic Peptide

The process of heparan sulfate proteoglycan (HSPG) internalization has been described as following different pathways. The tumor-specific branched NT4 peptide has been demonstrated to bind HSPGs on the plasma membrane and to be internalized in tumor cell lines. The polycationic peptide has been also...

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Detalles Bibliográficos
Autores principales: Mandarini, Elisabetta, Tollapi, Eva, Zanchi, Marta, Depau, Lorenzo, Pini, Alessandro, Brunetti, Jlenia, Bracci, Luisa, Falciani, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663799/
https://www.ncbi.nlm.nih.gov/pubmed/33167372
http://dx.doi.org/10.3390/ijms21218282