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Dual-Inhibitors of N-Myc and AURKA as Potential Therapy for Neuroendocrine Prostate Cancer

Resistance to androgen-receptor (AR) directed therapies is, among other factors, associated with Myc transcription factors that are involved in development and progression of many cancers. Overexpression of N-Myc protein in prostate cancer (PCa) leads to its transformation to advanced neuroendocrine...

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Detalles Bibliográficos
Autores principales: Ton, Anh-Tien, Singh, Kriti, Morin, Hélène, Ban, Fuqiang, Leblanc, Eric, Lee, Joseph, Lallous, Nada, Cherkasov, Artem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663809/
https://www.ncbi.nlm.nih.gov/pubmed/33167327
http://dx.doi.org/10.3390/ijms21218277