Priming with HDAC Inhibitors Sensitizes Ovarian Cancer Cells to Treatment with Cisplatin and HSP90 Inhibitors

Ovarian cancer is the fifth leading cause of cancer deaths. Chemoresistance, particularly against platinum compounds, contributes to a poor prognosis. Histone deacetylase inhibitors (HDACi) and heat shock protein 90 inhibitors (HSP90i) are known to modulate pathways involved in chemoresistance. This...

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Detalles Bibliográficos
Autores principales: Rodrigues Moita, Ana J., Bandolik, Jan J., Hansen, Finn K., Kurz, Thomas, Hamacher, Alexandra, Kassack, Matthias U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663919/
https://www.ncbi.nlm.nih.gov/pubmed/33167494
http://dx.doi.org/10.3390/ijms21218300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663919/
https://www.ncbi.nlm.nih.gov/pubmed/33167494
http://dx.doi.org/10.3390/ijms21218300

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