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Chitosan Oligosaccharides Suppress Nuclear Factor-Kappa B Activation and Ameliorate Experimental Autoimmune Uveoretinitis in Mice

We investigated the therapeutic potential and mechanism of chitosan oligosaccharides (COS) for experimental autoimmune uveoretinitis (EAU) in mice. EAU was induced in C57/BL6 mice by injection of human interphotoreceptor retinoid-binding protein (IRBP) peptides. At the same time, a high or low dose...

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Detalles Bibliográficos
Autores principales: Hsu, Sheng-Min, Yang, Chang-Hao, Tsai, Hsien-Yang, Lin, Chia-Jhen, Fang, Yi-Hsuan, Shieh, Chi-Chang, Chen, Shun-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664198/
https://www.ncbi.nlm.nih.gov/pubmed/33171990
http://dx.doi.org/10.3390/ijms21218326